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Home / Lyme Disease Research Highlights

Lyme Disease Research Highlights

Case Study: Lyme Disease with Erythema Migrans and Seventh Nerve Palsy in an African-American Man

Filed Under: Lyme Disease Research, Lyme Disease Research Highlights

Lyme Rash Near Armpit on African-American Man

Summary This case study describes an African-American male who was misdiagnosed for 7 weeks despite the patient exhibiting common symptoms and signs of Lyme disease (including EM rash and facial […]

The General Symptom Questionnaire-30 (GSQ-30): A Brief Measure of Multi-System Symptom Burden in Lyme Disease

Filed Under: Lyme Disease Research, Lyme Disease Research Highlights

Questionaire with Pen Being Filled Out

This study shows that the General Symptom Questionnaire-30 (GSQ-30) is a valid and reliable self-report instrument that clinicians and researchers could use to assess the multi-system symptom burden and response to treatment among patients with acute and post-treatment Lyme disease.

Measurement of Organ-Specific and Acute-Phase Blood Protein Levels in Early Lyme Disease

Filed Under: Lyme Disease Research, Lyme Disease Research Highlights

Measurement of Organ-Specific and Acute-Phase Blood Protein Levels in Early Lyme Disease

Summary Reliable blood biomarkers for the early diagnosis of Lyme disease are needed. This study takes a focused approach to analyze serum proteins of Lyme disease patients relative to healthy […]

Molecular testing of serial blood specimens from patients with early Lyme disease during antibiotic treatment reveals changing Borrelia burgdorferi genotypes

Filed Under: Lyme Disease Research, Lyme Disease Research Highlights

Molecular testing of serial blood specimens from patients with early Lyme disease during antibiotic treatment reveals changing Borrelia burgdorferi genotypes

This pilot study showed a direct molecular Lyme disease diagnostic test could be used to identify and genotype Borrelia burgdorferi during antibiotic treatment in early Lyme disease patients. Findings suggest that the host immune system or differential antibiotic susceptibility might have played a role in the observed genotypic shift.

Automated Detection of Erythema Migrans in early Lyme disease, and Other Confounding Skin Lesions, via Deep Learning

Filed Under: Lyme Disease Research, Lyme Disease Research Highlights Tagged With: Lyme, Lyme Disease, Lyme Research

Automated Detection of Erythema Migrans in early Lyme disease, and Other Confounding Skin Lesions, via Deep Learning

Recognition of the EM rash is crucial to early diagnosis and treatment. Improved rash recognition using deep learning methodology to prescreen patient rash photos may help prevent later serious manifestations of Lyme disease.

PET Imaging of Glial Activation in Patients with Post Treatment Lyme Disease

Filed Under: Lyme Disease Research, Lyme Disease Research Highlights Tagged With: Lyme Disease

PET Imaging of Glial Activation in Patients with Post Treatment Lyme Disease

This study uses a neuroimaging radiotracer with positron emission tomography (PET) to quantify cerebral glial activation in brains of patients with post-treatment Lyme disease. Results show elevated central nervous system immune activation in patients with PTLDS as compared to controls.

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