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Home / Research

Research

Molecular testing of serial blood specimens from patients with early Lyme disease during antibiotic treatment reveals changing Borrelia burgdorferi genotypes

Molecular testing of serial blood specimens from patients with early Lyme disease during antibiotic treatment reveals changing Borrelia burgdorferi genotypes

Summary This pilot study showed a direct molecular Lyme disease diagnostic test could be used to identify and genotype Borrelia burgdorferi during antibiotic treatment in early Lyme disease patients. Patients […]

Filed Under: News, Research

Automated Detection of Erythema Migrans in early Lyme disease, and Other Confounding Skin Lesions, via Deep Learning

Automated Detection of Erythema Migrans in early Lyme disease, and Other Confounding Skin Lesions, via Deep Learning

Recognition of the EM rash is crucial to early diagnosis and treatment. Improved rash recognition using deep learning methodology to prescreen patient rash photos may help prevent later serious manifestations of Lyme disease.

Filed Under: News, Research Tagged With: Lyme, Lyme Disease, Lyme Research

PET Imaging of Glial Activation in Patients with Post Treatment Lyme Disease

PET Imaging of Glial Activation in Patients with Post Treatment Lyme Disease

This study uses a neuroimaging radiotracer with positron emission tomography (PET) to quantify cerebral glial activation in brains of patients with post-treatment Lyme disease. Results show elevated central nervous system immune activation in patients with PTLDS as compared to controls.

Filed Under: News, Research Tagged With: Lyme Disease

Robust B Cell Responses Predict Rapid Resolution of Lyme Disease

Robust B Cell Responses Predict Rapid Resolution of Lyme Disease

Lyme disease (Borrelia burgdorferi infection) is increasingly recognized as a significant worldwide illness. This study provides insights into important immune mechanisms involved in Borrelia burgdorferi clearance in human Lyme disease.

Filed Under: News, Research Tagged With: Lyme Disease

Incidence of Lyme Disease Diagnosis in a Maryland Medicaid Population

Incidence of Lyme Disease Diagnosis in a Maryland Medicaid Population

This study evaluates overall incidence rates and demographic, seasonal, and geographic trends of first Lyme disease diagnosis among 384,652 Maryland Medicaid members enrolled from July 2004-June 2011 and represents the first analysis of claims data from publicly insured individuals.

Filed Under: News, Research Tagged With: Lyme Disease

Cognitive Decline in Post-treatment Lyme Disease Syndrome

Cognitive Decline in Post-treatment Lyme Disease Syndrome

Patients with Post-treatment Lyme Disease Syndrome (PTLDS) commonly complain of cognitive symptoms. The study found, in subsets of PTLDS patients, objective evidence of cognitive decline in verbal memory and processing speed, cognitive impairment, and sub-optimal engagement with testing.

Filed Under: News, Research Tagged With: Lyme Disease

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