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Home / Lyme Disease Research

Lyme Disease Research

Measurement of Organ-Specific and Acute-Phase Blood Protein Levels in Early Lyme Disease

Measurement of Organ-Specific and Acute-Phase Blood Protein Levels in Early Lyme Disease

Summary Reliable blood biomarkers for the early diagnosis of Lyme disease are needed. This study takes a focused approach to analyze serum proteins of Lyme disease patients relative to healthy […]

Filed Under: Lyme Disease Research, Lyme Disease Research News

Molecular testing of serial blood specimens from patients with early Lyme disease during antibiotic treatment reveals changing Borrelia burgdorferi genotypes

Molecular testing of serial blood specimens from patients with early Lyme disease during antibiotic treatment reveals changing Borrelia burgdorferi genotypes

This pilot study showed a direct molecular Lyme disease diagnostic test could be used to identify and genotype Borrelia burgdorferi during antibiotic treatment in early Lyme disease patients. Findings suggest that the host immune system or differential antibiotic susceptibility might have played a role in the observed genotypic shift.

Filed Under: Lyme Disease Research, Lyme Disease Research News

Automated Detection of Erythema Migrans in early Lyme disease, and Other Confounding Skin Lesions, via Deep Learning

Automated Detection of Erythema Migrans in early Lyme disease, and Other Confounding Skin Lesions, via Deep Learning

Recognition of the EM rash is crucial to early diagnosis and treatment. Improved rash recognition using deep learning methodology to prescreen patient rash photos may help prevent later serious manifestations of Lyme disease.

Filed Under: Lyme Disease Research, Lyme Disease Research News Tagged With: Lyme, Lyme Disease, Lyme Research

PET Imaging of Glial Activation in Patients with Post Treatment Lyme Disease

PET Imaging of Glial Activation in Patients with Post Treatment Lyme Disease

This study uses a neuroimaging radiotracer with positron emission tomography (PET) to quantify cerebral glial activation in brains of patients with post-treatment Lyme disease. Results show elevated central nervous system immune activation in patients with PTLDS as compared to controls.

Filed Under: Lyme Disease Research, Lyme Disease Research News Tagged With: Lyme Disease

Robust B Cell Responses Predict Rapid Resolution of Lyme Disease

Robust B Cell Responses Predict Rapid Resolution of Lyme Disease

Lyme disease (Borrelia burgdorferi infection) is increasingly recognized as a significant worldwide illness. This study provides insights into important immune mechanisms involved in Borrelia burgdorferi clearance in human Lyme disease.

Filed Under: Lyme Disease Research, Lyme Disease Research News Tagged With: Lyme Disease

Incidence of Lyme Disease Diagnosis in a Maryland Medicaid Population

Incidence of Lyme Disease Diagnosis in a Maryland Medicaid Population

This study evaluates overall incidence rates and demographic, seasonal, and geographic trends of first Lyme disease diagnosis among 384,652 Maryland Medicaid members enrolled from July 2004-June 2011 and represents the first analysis of claims data from publicly insured individuals.

Filed Under: Lyme Disease Research, Lyme Disease Research News Tagged With: Lyme Disease

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