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Home / Lyme Disease Research

Lyme Disease Research

Lyme Disease in the Era of COVID-19: A Delayed Diagnosis and Risk for Complications

Lyme Disease in the Era of COVID-19: A Delayed Diagnosis and Risk for Complications

This report presents a Lyme disease case that was initially misdiagnosed in the spring of 2020 resulting in disseminated infection and sixth nerve palsy and highlights new challenges facing healthcare delivery in the era of COVID-19. The objective of this report is to describe the obstacles for diagnosticians during the pandemic and also to discuss the potential beneficial application of telemedicine in the early diagnosis of Lyme disease during the COVID-19 era as well as in the future.

Filed Under: Lyme Disease Research, Lyme Disease Research Highlights

The presenting characteristics of the Lyme disease erythema migrans rash vary by age, sex, duration, and body location

The presenting characteristics of the Lyme disease erythema migrans rash vary by age, sex, duration, and body location

The erythema migrans (EM) rash, when present, is often the first clinical sign of Lyme disease. This study shows that EM presentations vary with age, sex, EM duration, body location, and timing of initiation of antibiotics. Understanding this EM variability can help physicians and the general public better recognize the rash and improve early diagnosis and treatment.

Filed Under: Lyme Disease Research, Lyme Disease Research Highlights

An observational study of symptom heterogeneity and patient subgroup classification among US patients with post-treatment Lyme disease

An observational study of symptom heterogeneity and patient subgroup classification among US patients with post-treatment Lyme disease

This study examines heterogeneity in symptom reporting in patients with well-defined post treatment Lyme disease (PTLD) in order to identify and characterize clinically relevant patient subgroups.

Filed Under: Lyme Disease Research, Lyme Disease Research Highlights

Metabolic Response in Patients with Post-Treatment Lyme Disease

Metabolic Response in Patients with Post-Treatment Lyme Disease

Objective metabolite-based measurements differ between Lyme disease patients that develop persistent symptoms following antibiotic treatment (PTLD) and those that are clinically cured. These differences could be useful in better identifying, differentiating, and understanding the underlying biochemistry of patients with persistent symptoms in Lyme disease.

Filed Under: Lyme Disease Research, Lyme Disease Research Highlights

Lyme disease bacteria induce changes in self-immunopeptides expressed by dendritic cells

Lyme disease bacteria induce changes in self-immunopeptides expressed by dendritic cells

Lyme disease infection and genetic susceptibility to autoimmune diseases may trigger breakdown in tolerance to self-antigens & contribute to dysregulated immunity, autoimmune illness, & persistent symptoms

Filed Under: Lyme Disease Research, Lyme Disease Research Highlights

An artificial intelligence and deep learning-based approach can improve the early detection of the Lyme disease rash

An artificial intelligence and deep learning-based approach can improve the early detection of the Lyme disease rash

Summary This study shows that artificial intelligence (AI) and deep learning (DL) methods can be used to analyze cell phone rash images to more accurately detect and prescreen the erythema […]

Filed Under: Lyme Disease Research, Lyme Disease Research Highlights

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